Category Archive: NEJM

Metastasis-free Survival — A New End Point in Prostate Cancer Trials

Earlier this year, the Food and Drug Administration (FDA) approved apalutamide, an androgen receptor inhibitor, for treatment of patients with nonmetastatic castration-resistant prostate cancer (nmCRPC). The approval was based on SPARTAN, a randomized,…

Making Neighborhood-Disadvantage Metrics Accessible — The Neighborhood Atlas

Health disparities are a major problem in the United States: many conditions, including cardiovascular disease, diabetes, and Alzheimer’s disease, disproportionately affect racial and ethnic minorities and the socioeconomically disadvantaged. Few inter…

Firearm Injuries and Violence Prevention — The Potential Power of a Surgeon General’s Report

In the aftermath of the mass shooting at a social services center in San Bernardino, California, in 2015, President Barack Obama suggested that the relationship between firearm ownership and gun injuries might be as strong as the connection between cig…

Accreditation of Clinical Research Sites — Moving Forward

Accreditation is used in many fields, including education, travel, construction, and health care. When implemented correctly, it improves quality, performance, and safety, while signaling to the public that an accredited entity is committed to an agree…

The Suffering of Children

Every pediatrician has his or her own tips for putting young patients at ease in the exam room. Mine include referring to even the tiniest Spanish-speaking patients as usted rather than tú, as a sign of respect, and sitting at or below their level to a…

Housing Immigrant Children — The Inhumanity of Constant Illumination

On the Wednesday before the summer solstice in the United States, President Donald Trump ended his administration’s policy of forced separation of immigrant children from their parents at the U.S.–Mexico border — a practice characterized by the preside…

Why the VA Needs More Competition

Despite independent studies showing that clinical quality in the Department of Veterans Affairs (VA) health system is often as good as or better than that in the private sector, numerous areas for improvement remain. Moreover, going forward, VA reform …

Growing Ranks of Advanced Practice Clinicians — Implications for the Physician Workforce

Throughout the history of modern American medicine, physicians have made up the vast majority of professionals who diagnose, treat, and prescribe medication to patients. Although demand for medical services has increased markedly over the years (and is…

Informed Consent and the Role of the Treating Physician

In the century since Justice Benjamin N. Cardozo famously declared that “[e]very human being of adult years and sound mind has a right to determine what shall be done with his own body,” informed consent has become a central feature of American medical…

The Graduate Nurse Education Demonstration — Implications for Medicare Policy

Despite decades of public and private investment, the United States continues to have a shortage of primary care capacity. Only 2699 graduating U.S. medical students — about 17% of graduates from allopathic and osteopathic schools — matched with primar…

Older posts «

» Newer posts

Explore the Archive