Physicians’ entrepreneurial spirit: 6 things to know

Under half of physicians (38%) are currently involved in an entrepreneurial venture, or are considering one, outside of their traditional work, according to Medscape’s 2025 “‘I Get to Be Creative Again — That’s the Juice’: Medscape Physicians as Entrepreneurs Report 2025,” report, published June 13. 

Here are six things to know about physicians’ entrepreneurial ventures: 

1. Over half of physicians who are involved in entrepreneurial ventures, 53%, are involved ventures outside of the medical field. 

2. Nearly half of physicians with entrepreneurial ventures plan to (25%), or are considering (33%), leaving medicine for their new business. 

3. Nearly half of physicians with entrepreneurial ventures (40%) serve as either sole proprietor or executive leader of the project. 

4. Over half of physicians are at least somewhat confident that their ventures will succeed. While just 14% are very confident, an additional 35% are confident and 34% are somewhat confident. 

5. Over half of physicians (59%) anticipate profitability in their venture within three years. 

6. Over half of physicians (57%) plan to eventually sell off their venture.

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