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39-year-old woman with fatigue, intermittent rectal bleeding, and abdominal pain

Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 39-year-old woman is evaluated for fatigue, intermittent rectal bleeding, and abdominal pain over the past 2 months. She reports that the b…

MKSAP: 52-year-old woman with shortness of breath

Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 52-year-old woman is evaluated during a follow-up visit. She was discharged from the hospital 3 weeks ago following a small non–ST-elevatio…

MKSAP: 60-year-old man with constant low-grade epigastric pain radiating to his back

Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 60-year-old man is evaluated for constant low-grade epigastric pain radiating to his back that worsens after he eats fatty foods. He has a …

MKSAP: 49-year-old woman with worsening joint symptoms

Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 49-year-old woman is evaluated for recently worsening joint symptoms. She has a 13-year history of Crohn disease characterized by four to s…

MKSAP: 79-year-old man with headaches, nausea, visual disturbance, and difficulty speaking

Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 79-year-old man is evaluated for a 2-month history of progressively worsening headaches, nausea, visual disturbance, and difficulty speakin…

MKSAP: 40-year-old man with a new skin rash of 10 days’ duration

Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 40-year-old man is evaluated for a new skin rash of 10 days’ duration. The rash appeared abruptly and is not tender or pruritic. The …

MKSAP: 81-year-old woman with headaches, redness of the face, and itching

Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. An 81-year-old woman is evaluated for a 1-year history of headaches, redness of the face, and itching. She indicates being otherwise capable …

MKSAP: 75-year-old man with progressive dysphagia

Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 75-year-old man is evaluated for progressive dysphagia of 8 months’ duration for both solid food and water, and the necessity to indu…

Eradication of H. Pylori should be confirmed using the urea breath test or fecal antigen test

Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 60-year-old woman is evaluated 1 month after completing a 14-day course of Helicobacter pylori eradication therapy consisting of amoxicilli…

MKSAP: 32-year-old man with an intermittent pruritic rash

Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 32-year-old man is evaluated for an intermittent pruritic rash of 8 years’ duration. Medical history is significant for mild persiste…