William A. Haseltine, Contributor

Author's posts

Is A Universal Influenza Vaccine— One Shot For All Strains— On The Horizon?

Flu vaccines need to be readministered every year to keep pace with viral mutations. “Universal vaccines” could change this. Here, we describe a recent success in the development of a universal influenza A vaccine.

Waiting In The Wings: A Potential New Variant Of SARS-CoV-2

A new member of the Omicron family, BA.2.75.2, shows potential as the next major variant of the Covid-19 pandemic.

SARS-CoV-2 Main Protease Suppresses Innate Immunity By Cleaving Proteins Required For Interferon Induction And Inflammation

In addition to cleaving virus proteins, SARS-CoV-2 main protease released into the host cell has the potential to cleave cellular proteins.

Getting a Grip on Influenza: The Pursuit of a Universal Vaccine (Part 5)

Flu vaccines need to be readministered every year to keep pace with viral mutations. “Universal vaccines” could change this, providing us with a much broader immunity that remains effective even in the face of constant variation. How do they work?

Reimagining Alzheimer’s (Part 1)

Recent discoveries in Alzheimer’s disease research have thrown into question fundamental assumptions about the disease and its origins. In the first installment of our series, we offer a brief overview of Alzheimer’s disease.

Will The BA.4.6 Variant Drive The Next Wave Of The Covid-19 Pandemic?

We draw attention to a variant, BA.4.6, which has the potential to trigger the next wave.

Nasal Vaccines May Not Be The Game Changer We Think They Are

Many are pinning their hopes on nasal vaccines becoming the tool that finally halts transmission of the Covid-19 virus. I do not share the same unbridled enthusiasm that nasal vaccines will provide long-lasting protection from infection and protection …

Molecular Jujitsu: SARS-CoV-2 Co-Opts Host Defense

A recent study shows how the SARS-CoV-2 N protein can co-opt a component of the host’s defense to suppress host immunity

Progress In The Search For Broadly Neutralizing Monoclonal Antibodies VIII

The MO1 antibody strongly and broadly neutralizes SARS-CoV-2 variants, including the latest versions of Omicron – BA.5 and BA.2.75.

Getting a Grip on Influenza: The Pursuit of a Universal Vaccine (Part 4)

Mucosal vaccines have been a source of a lot of excitement in recent years. How are they different from your usual flu vaccine, and are they more effective?