William A. Haseltine, Contributor

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Functions Of SARS-CoV-2 NSP13 Helicase: Replication, Transcription, And Suppression Of Natural Immunity

A new study sheds light on one of the roles SARS-CoV-2 NSP13 (nonstructural protein 13) plays in the virus’ initial attack on the immune system, which is to degrade a kinase enzyme upstream of interferon, TBK1 (TANK-binding kinase 1).

Functions Of SARS-CoV-2 NSP12 Polymerase: Replication, Transcription, And Suppression Of Natural Immunity

In February 2021, a paper published in Cellular & Molecular Immunology confirmed that NSP12 suppresses the activity of a coding gene, IRF3 (interferon regulatory factor 3), key to the production of interferon.

Birth Of The Omicron Family: BA.1, BA.2, BA.3. Each As Different As Alpha Is From Delta.

Here, we introduce the Omicron family of variants. More detailed descriptions of each strain will follow this introduction. In this first entry, we will introduce the three, how they diverged from the Wuhan strain, and how they compare to each other.

New Clues To Long Covid: Prolonged Inflammatory Response

Long Covid patients show signs of sustained inflammation and immune response activation for at least 8 months after initial infection.

The Danger Of Covid-19 Monotherapy: Drug Resistance

The current protocol for Omicron infections dictates that patients are treated with either one monoclonal antibody preparation or one antiviral drug. This is not an optimal strategy but instead, one necessitated by current drug approvals. Unfortunately…

Novel Antiviral Approach To Covid-19 Treatment

New antiviral drug, developed by Novartis and Molecular Partners, built to resist viral mutations and variants.

Novel Antiviral Approach To Covid-19 Treatment

New antiviral drug, developed by Novartis and Molecular Partners, built to resist viral mutations and variants.

Major Protease Of SARS-CoV-2 Acts To Suppress Innate Immunity

In October 2020, researchers discovered that the SARS-CoV-2 nonstructural protein 5 (NSP5) suppresses innate immunity. This has key implications for Covid-19 drug development that have yet to be fully explored.

Major Protease Of SARS-CoV-2 Acts To Suppress Innate Immunity

In October 2020, researchers discovered that the SARS-CoV-2 nonstructural protein 5 (NSP5) suppresses innate immunity. This has key implications for Covid-19 drug development that have yet to be fully explored.

New Data Suggests That 50% Of Omicron Infections In Healthy Young Men Remain Transmissible After Five Days

The study gathered PCR tests from basketball players in the National Basketball Association, aiming to elucidate the viral dynamics of Omicron, namely when viral load peaks and how long the general infection lasts.