Unique changes in the Omicron family of variant Spike protein structure enable its enhanced viral characteristics.
Category: pharma & healthcare
Study Shows Unvaccinated People Are At Increased Risk Of Infecting The Vaccinated
A new modeling study published in the Canadian Medical Association Journal demonstrates that unvaccinated people threaten the safety of the vaccinated even when SARS-Cov-2 vaccination rates are high.
ICER’s Favorable Assessment Of Bluebird Bio’s Gene Therapy Zynteglo May Have Important Pricing And Reimbursement Implications
A June FDA advisory committee will be a huge moment for struggling bluebird bio. A positive decision by FDA coupled with the favorable ICER assessment could lead to a robust cash flow. Being considered cost-effective may offer Zynteglo a distinct advan…
FDA Commissioner Califf Says Business Of Health Is Booming In U.S. But Patients’ Outcomes Aren’t Improving
“I think that is an American problem right now,” Califf asserted, noting that the business of healthcare has never been better, but the outcomes of the people the system is trying to serve are not getting better.
Structural Analysis Of The Omicron Spike Unveils Houdini-Like Immune Escape
Here we analyze some of the structural properties of Omicron that enable efficient immune escape.
New Research Provides Hope In The Search For A Respiratory Syncytial Virus Vaccine- Part II
Respiratory syncytial virus is one of the leading causes of death for infants globally, and a safe vaccine has yet to be approved for use. However, the long search may soon be over, as new structure-based vaccine technology holds great promise.
Covid-19 Has Made Tuberculosis Even More Of A Forgotten Pandemic
The impact of the Covid-19 pandemic goes well beyond the disease itself. It extends to neglected tropical diseases, as well as the big three infectious diseases malaria, HIV/AIDS, and tuberculosis, by crowding out R&D funds and disrupting non-Covid-19 …
Far-Ultraviolet Light Is Another Way To Keep Our Public Spaces Safe
For some time now, it’s been established that the primary root of SARS-CoV-2 transmission is airborne. Here we describe work that shows, in addition to ventilation and filtration, how Far-UVC light inactivates the virus in a way that is harmless to us.
Asthma Medication Points The Way To Drugs To Prevent And Treat Covid-19: Nsp1, A Novel Target
Montelukast, an asthma drug, can bind to and block a crucial SARS-CoV-2 protein. This discovery sets the stage for a new class of antiviral drugs, designed to target and interfere with the virus’ immunosuppressive tactics.
CMS’s Decision To Restrict Coverage Of Aduhelm Very Unlikely To Impact Other Accelerated Approvals In Other Classes
One could argue that CMS is restricting coverage of a particular instance of an accelerated approval and a set of potential approvals for a narrowly defined sub-class of beta amyloid-directed monoclonal antibodies. And this particular decision has no u…
