Category: pharma & healthcare

The Mystery Of The False Start At The 5’ End Of SARS-CoV-2

There is a short string of nucleotides in SARS-CoV-2, as well as most coronaviruses, that has the potential to initiate protein synthesis between 150 and 200 nucleotides prior to the initiation of the first major protein in the virus, Orf1a.

Ivermectin, A 40-Year Old Anti-Parasitic Now Embedded In A Covid-19 Culture War

The fact that ivermectin has become a lightning rod embedded in a Covid-19 culture war should surprise no-one. The pandemic has been replete with politicized discussions of non-pharmaceutical interventions, treatments, vaccines, and even the virus itse…

How SARS-CoV-2 Evades And Suppresses The Immune System (Part 8)

SARS-CoV-2 blocks expression of almost all cellular genes and proteins to favor its own messenger RNA and protein synthesis.

How The Pandemic Is Fueling Eating Disorders In Young People

The pandemic has triggered a surge of new eating disorders and relapses in young people. Many of these young people are still struggling without access to treatment.

Depression And Anxiety Double In Youth Compared To Pre-Pandemic

A new meta-analysis from the University of Calgary, showing that depression and anxiety symptoms have doubled in children and adolescents globally when compared to pre-pandemic times.

How SARS-CoV-2 Evades And Suppresses The Immune System (Part 7)

SARS-CoV-2 mechanisms of immune suppression can be generally described as either specific or nonspecific. Learning about them unlocks opportunities for Covid-19 drug development.

4,700 People Positive For Covid-19 After Superspreader Music Festival

Almost 1 in 10 people who were at the event in England have now tested positive for Covid-19.

Decoding The Gordian Knots At The Ends Of The SARS-CoV-2 Genome

The bookends of the viral genome are responsible for many of the virus’s critical functions, including initiation of replication, protein synthesis, and messenger RNA synthesis.

Babies And Toddlers Are Highly Contagious For Covid-19

A new study by Public Health Ontario, finds that infants and toddlers (0-3 years) are less likely to bring SARS-CoV-2 into the home but are more likely to transmit SARS-CoV-2 compared with older children (14-17 years).

How SARS-CoV-2 Evades And Suppresses The Immune System (Part 6)

Not only does the Covid-19 virus have to conceal its replication activity via a double membrane vesicle, it must also camouflage viral messenger RNAs so they evade immune detection.